Fasting, the greatest known boost to autophagy by Michael Cummins, Fri 22 Dec '17

Fasting, the greatest known boost to autophagy

"Nutrient deprivation is the key activator of autophagy. Remember that glucagon is kind of the opposite hormone to insulin. It’s like the game we played as kids – 'opposite day'. If insulin goes up, glucagon goes down. If insulin goes down, glucagon goes up. As we eat insulin goes up and glucagon goes down. When we don’t eat (fast) insulin goes down and glucagon goes up. This increase in glucagon stimulates the process of autophagy. In fact, fasting (raises glucagon) provides the greatest known boost to autophagy."

Dr. Jason Fung, M.D., nephrologist, in Fasting and Autophagy – Fasting 25

 

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